Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies
Abstract Background A cationic liposome-PEG-PEI complex (LPPC) was employed as a carrier for achieving targeted delivery of drug to human epidermal growth factor receptor-2 (HER2/neu)-expressing breast cancer cells. LPPC can be easily loaded with an anti-tumor drug and non-covalently associated with...
Main Authors: | Yu-Ling Lin, Nu-Man Tsai, Chia-Hung Chen, Yen-Ku Liu, Chung-Jen Lee, Yi-Lin Chan, Yu-Shan Wang, Yuan-Ching Chang, Chi-Hsin Lin, Tse-Hung Huang, Chao Ching Wang, Kwan-Hwa Chi, Kuang-Wen Liao |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12951-019-0457-3 |
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