NREM delta power and AD-relevant tauopathy are associated with shared cortical gene networks

Abstract Reduced NREM sleep in humans is associated with AD neuropathology. Recent work has demonstrated a reduction in NREM sleep in preclinical AD, pointing to its potential utility as an early marker of dementia. We test the hypothesis that reduced NREM delta power and increased tauopathy are ass...

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Bibliographic Details
Main Authors: Joseph R. Scarpa, Peng Jiang, Vance D. Gao, Martha H. Vitaterna, Fred W. Turek, Andrew Kasarskis
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86255-6