The GDNF System Is Altered in Diverticular Disease - Implications for Pathogenesis.

The GDNF System Is Altered in Diverticular Disease - Implications for Pathogenesis.

Absence of glial cell line-derived neurotrophic factor (GDNF) leads to intestinal aganglionosis. We recently demonstrated that patients with diverticular disease (DD) exhibit hypoganglionosis suggesting neurotrophic factor deprivation. Thus, we screened mRNA expression pattern of the GDNF system in...

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Bibliographic Details
Main Authors: Martina Böttner, Martina Barrenschee, Ines Hellwig, Jonas Harde, Jan-Hendrik Egberts, Thomas Becker, Dimitri Zorenkov, Karl-Herbert Schäfer, Thilo Wedel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689736?pdf=render

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http://europepmc.org/articles/PMC3689736?pdf=render

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