β-amyloid oligomers in aging and Alzheimer's disease

Alzheimer’s disease (AD) is a fatal neurodegenerative disorder, and the most common cause of dementia in the elderly. The cause of AD is not known, but genetic evidence strongly supports the hypothesis that pathological aggregation of the β-amyloid protein (Aβ) triggers the disease process. AD has...

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Bibliographic Details
Main Authors: Kathleen R. Zahs, Karen Hsiao Ashe
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00028/full