High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.

High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.

Antibodies are assembled by a highly orchestrated series of recombination events during B cell development. One of these events, class switch recombination, is required to produce the IgG, IgE and IgA antibody isotypes characteristic of a secondary immune response. The action of the enzyme activatio...

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Bibliographic Details
Main Authors: Sandeep Dayal, Jakub Nedbal, Philip Hobson, Alison M Cooper, Hannah J Gould, Martin Gellert, Gary Felsenfeld, David J Fear
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176761?pdf=render

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http://europepmc.org/articles/PMC3176761?pdf=render

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