Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma.

Cancer stem-like cells (CSCs) have been reported to play major roles in tumorigenesis, tumor relapse, and metastasis after therapy against colorectal carcinoma (CRC). Therefore, identification of colorectal CSC regulators could provide promising targets for CRC. Ligand-of-Numb protein X1 (LNX1) is o...

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Bibliographic Details
Main Authors: Lin Ma, Lan Wang, Yating Shan, Muhammad Nafees, Elshoura Ihab, Ruhui Zhang, Fangjun Wang, Wu Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708683?pdf=render