Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy

Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy

To elucidate the previously suggested vascular effect(s) of antiestrogen therapy, we studied the effect of estrogen withdrawal and tamoxifen on 1) vascular resistance, 2) glucose and oxygen consumption, 3) vascular density in a perfused breast cancer line (ZR751). Furthermore, we examined ZR75-1 tu...

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Bibliographic Details
Main Authors: Claus A. Kristensen, Leena M. Hamberg, George J. Hunter, Sylvie Roberge, Diane Kierstead, Gerald L. Wolf, Rakesh K. Jain
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
vascular resistance
estrogen withdrawal
tamoxifen
breast cancer
functional CT-scanning
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800050

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http://www.sciencedirect.com/science/article/pii/S1476558699800050

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