Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy

Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy

The etiology of Ankylosing spondylitis (AS) is still unknown and the identification of the involved molecular pathogenetic pathways is a current challenge in the study of the disease. Adalimumab (ADA), an anti-tumor necrosis factor (TNF)-alpha agent, is used in the treatment of AS. We aimed at ident...

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Bibliographic Details
Main Authors: Marzia Dolcino, Elisa Tinazzi, Andrea Pelosi, Giuseppe Patuzzo, Francesca Moretta, Claudio Lunardi, Antonio Puccetti
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Genes
Subjects:
Ankylosing spondylitis
Adalimumab (ADA)
gene-array
protein-protein interaction (PPI) network
gene module
Online Access:http://www.mdpi.com/2073-4425/8/4/127

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http://www.mdpi.com/2073-4425/8/4/127

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