Molecular characterization of exploitation of the polyubiquitination and farnesylation machineries of Dictyostelium discoideum by the AnkB F-box effector of Legionella pneumophila

Molecular characterization of exploitation of the polyubiquitination and farnesylation machineries of Dictyostelium discoideum by the AnkB F-box effector of Legionella pneumophila

The Dot/Icm-translocated Ankyrin B (AnkB) F-box effector of L. pneumophila is essential for intra-vacuolar proliferation and functions as a platform for the docking of polyubiquitinated proteins to the Legionella-containing vacuole (LCV) within macrophages and amoeba. Here we show that ectopically e...

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Bibliographic Details
Main Authors: Yousef eAbu Kwaik, Tasneem eAl-Quadan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Dot/Icm
franesylation
LCV
Legionnaires'
polyubiquitination
SCF1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00023/full

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