Role of vegetation-associated protease activity in valve destruction in human infective endocarditis.

AIMS: Infective endocarditis (IE) is characterized by septic thrombi (vegetations) attached on heart valves, consisting of microbial colonization of the valvular endocardium, that may eventually lead to congestive heart failure or stroke subsequent to systemic embolism. We hypothesized that host def...

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Bibliographic Details
Main Authors: Ghada Al-Salih, Nawwar Al-Attar, Sandrine Delbosc, Liliane Louedec, Elisabeth Corvazier, Stéphane Loyau, Jean-Baptiste Michel, Dominique Pidard, Xavier Duval, Olivier Meilhac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447824?pdf=render