Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A<sub>1</sub> and A<sub>2A</sub> Receptors

Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A<sub>1</sub> and A<sub>2A</sub> Receptors

Acute or chronic administration of guanosine (GUO) induces anxiolytic-like effects, for which the adenosine (ADO) system involvement has been postulated yet without a direct experimental evidence. Thus, we aimed to investigate whether adenosine receptors (ARs) are involved in the GUO-mediated anxiol...

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Bibliographic Details
Main Authors: Monica Frinchi, Vincenzo Verdi, Fulvio Plescia, Francisco Ciruela, Maria Grillo, Roberta Garozzo, Daniele F. Condorelli, Patrizia Di Iorio, Francesco Caciagli, Renata Ciccarelli, Natale Belluardo, Valentina Di Liberto, Giuseppa Mudò
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
guanosine
adenosine
behavior
A<sub>1</sub>R
A<sub>2A</sub>R
caffeine
Online Access:https://www.mdpi.com/1422-0067/21/23/9281

Internet

https://www.mdpi.com/1422-0067/21/23/9281

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