A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.

A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.

Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of cell divisions remain poorly characterized. Here we describe a screen of a collection of 3762 single gene mutants in the yeast Saccharomyces ce...

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Bibliographic Details
Main Authors: Ata Ghavidel, Kunal Baxi, Vladimir Ignatchenko, Martin Prusinkiewicz, Terra G Arnason, Thomas Kislinger, Carlos E Carvalho, Troy A A Harkness
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4527830?pdf=render

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http://europepmc.org/articles/PMC4527830?pdf=render

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