Monoallelic expression in melanoma

Monoallelic expression in melanoma

Abstract Background Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence of a diploid heterozygous genome. Constitutive MA...

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Bibliographic Details
Main Authors: Lee Silcock, Hakeem Almabrazi, Younes Mokrab, Puthen Jithesh, Muna Al-Hashmi, Nicola James, Rebecca Mathew, Valentina Mattei, Davide Bedognetti, Francesca Lessi, Ramzi Temanni, Barbara Seliger, Rashid Al-Ali, Francesco M. Marincola, Ena Wang, Sara Tomei
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Monoallelic expression
Melanoma
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s12967-019-1863-x

Internet

http://link.springer.com/article/10.1186/s12967-019-1863-x

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