Identification of Novel Candidate Markers of Type 2 Diabetes and Obesity in Russia by Exome Sequencing with a Limited Sample Size

Identification of Novel Candidate Markers of Type 2 Diabetes and Obesity in Russia by Exome Sequencing with a Limited Sample Size

Type 2 diabetes (T2D) and obesity are common chronic disorders with multifactorial etiology. In our study, we performed an exome sequencing analysis of 110 patients of Russian ethnicity together with a multi-perspective approach based on biologically meaningful filtering criteria to detect novel can...

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Bibliographic Details
Main Authors: Yury A. Barbitoff, Elena A. Serebryakova, Yulia A. Nasykhova, Alexander V. Predeus, Dmitrii E. Polev, Anna R. Shuvalova, Evgenii V. Vasiliev, Stanislav P. Urazov, Andrey M. Sarana, Sergey G. Scherbak, Dmitrii V. Gladyshev, Maria S. Pokrovskaya, Oksana V. Sivakova, Aleksey N. Meshkov, Oxana M. Drapkina, Oleg S. Glotov, Andrey S. Glotov
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Genes
Subjects:
type 2 diabetes
obesity
next-generation sequencing
exome sequencing
susceptibility locus
single nucleotide polymorphisms
association study
Online Access:http://www.mdpi.com/2073-4425/9/8/415

Internet

http://www.mdpi.com/2073-4425/9/8/415

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