SLIDR and SLOPPR: flexible identification of spliced leader trans-splicing and prediction of eukaryotic operons from RNA-Seq data

SLIDR and SLOPPR: flexible identification of spliced leader trans-splicing and prediction of eukaryotic operons from RNA-Seq data

Abstract Background Spliced leader (SL) trans-splicing replaces the 5′ end of pre-mRNAs with the spliced leader, an exon derived from a specialised non-coding RNA originating from elsewhere in the genome. This process is essential for resolving polycistronic pre-mRNAs produced by eukaryotic operons...

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Bibliographic Details
Main Authors: Marius A. Wenzel, Berndt Müller, Jonathan Pettitt
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Bioinformatics
Subjects:
Spliced-leader trans-splicing
Eukaryotic operons
Polycistronic RNA processing
RNA-seq
Genome annotation
Chimeric reads
Online Access:https://doi.org/10.1186/s12859-021-04009-7

Internet

https://doi.org/10.1186/s12859-021-04009-7

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