Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in <it>Aspergillus niger</it> reveals a coordinated cellular response to counteract ER stress

Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in <it>Aspergillus niger</it> reveals a coordinated cellular response to counteract ER stress

<p>Abstract</p> <p>Background</p> <p>HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced...

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Bibliographic Details
Main Authors: Carvalho Neuza DSP, Jørgensen Thomas R, Arentshorst Mark, Nitsche Benjamin M, van den Hondel Cees AMJJ, Archer David B, Ram Arthur FJ
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Genomics
Subjects:
HacA
Unfolded protein response
Secretion stress
RESS
XBP1
<it>Aspergillus niger</it>
Protein secretion
Online Access:http://www.biomedcentral.com/1471-2164/13/350

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http://www.biomedcentral.com/1471-2164/13/350

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