Pharmacokinetic/Pharmacodynamic Modeling of Tulathromycin against Pasteurella multocida in a Porcine Tissue Cage Model

Tulathromycin, a macrolide antibiotic, is used for the treatment of respiratory disease in cattle and swine. The aim of our study was to investigate the in vitro and ex vivo activities of tulathromycin in serum, (non-inflamed) transudate, and (inflamed) exudate against Pasteurella multocida in pigle...

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Bibliographic Details
Main Authors: Qiaoyi Zhou, Guijun Zhang, Qin Wang, Wenguang Liu, Yan Huang, Pengling Yu, Yanqin Li, Huanzhong Ding, Binghu Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00392/full