Differential regulation of IFNα, IFNβ and IFNε gene expression in human cervical epithelial cells

Abstract Interferonε (IFNε) is a unique type I IFN that has distinct functions from IFNα/β. IFNε is constitutively expressed at mucosal tissues, including the female genital mucosa, and is reported to be modulated by estrogen and seminal plasma. However, its regulation by cytokines, including TNFα,...

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Bibliographic Details
Main Authors: Jennifer Couret, Carley Tasker, Jaeha Kim, Tiina Sihvonen, Saahil Fruitwala, Alison J. Quayle, Pierre Lespinasse, Debra S. Heller, Theresa L. Chang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cell & Bioscience
Online Access:http://link.springer.com/article/10.1186/s13578-017-0185-z