Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents

This work describes the synthesis of seven new platinum complexes having Nbenzyl 1,3-propanediamine derivatives as ligands. They were prepared by the reaction of K2[PtCl4] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.

Bibliographic Details
Main Authors: José Dias de Souza Filho, Emanoel de Castro Antunes Felício, Eloi Teixeira César, Richard Nilton Berg, Ana Paula Soares Fontes, Mauro Vieira de Almeida
Format: Article
Language:English
Published: MDPI AG 2002-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/7/4/405/