Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

Stochastic and deterministic allele specific gene expression (ASE) might influence single cell phenotype, but the extent and nature of the phenomenon at the onset of early mouse development is unknown. Here we performed single cell RNA-Seq analysis of single blastomeres of mouse embryos, which revea...

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Bibliographic Details
Main Authors: Fuchou Tang, Catalin Barbacioru, Ellen Nordman, Siqin Bao, Caroline Lee, Xiaohui Wang, Brian B Tuch, Edith Heard, Kaiqin Lao, M Azim Surani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3121735?pdf=render

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http://europepmc.org/articles/PMC3121735?pdf=render

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