Multiplexed peptide analysis for kinetic measurements of major human apolipoproteins by LC/MS/MS[S]

Multiplexed peptide analysis for kinetic measurements of major human apolipoproteins by LC/MS/MS[S]

A multiplexed assay was developed by MS to analyze, in a single run, six major human Apos involved in lipoprotein metabolism: ApoA-I, ApoA-II, ApoB100, ApoC-II, ApoC-III, and ApoE. This method was validated in vivo in six subjects who received a 14 h constant infusion of [5,5,5-2H3]L-leucine at 10 μ...

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Bibliographic Details
Main Authors: Mikaël Croyal, Fanta Fall, Véronique Ferchaud-Roucher, Maud Chétiveaux, Yassine Zaïr, Khadija Ouguerram, Michel Krempf, Estelle Nobécourt
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Lipid Research
Subjects:
lipoproteins/metabolism
lipoproteins/kinetics
nutrition protein
multiplexed assay
stable isotope
liquid chromatography-tandem mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752035450X

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http://www.sciencedirect.com/science/article/pii/S002222752035450X

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