Effective Activation of BK<sub>Ca</sub> Channels by QO-40 (5-(Chloromethyl)-3-(Naphthalen-1-yl)-2-(Trifluoromethyl)Pyrazolo [1,5-a]pyrimidin-7(4<i>H</i>)-one), Known to Be an Opener of KCNQ2/Q3 Channels
QO-40 (5-(chloromethyl)-3-(naphthalene-1-yl)-2-(trifluoromethyl) pyrazolo[1,5-a]pyrimidin-7(4<i>H</i>)-one) is a novel and selective activator of KCNQ2/KCNQ3 K<sup>+</sup> channels. However, it remains largely unknown whether this compound can modify any other type of plasmal...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/14/5/388 |