Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells

Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells

Tumor-induced immunosuppressive microenvironment in which myeloid-derived suppressor cells (MDSCs) plays an important role, remains an obstacle for effective oncotherapy currently. Inducing MDSCs into maturation was confirmed as an effective method to reduce the tumor-bearing host's immunosuppr...

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Bibliographic Details
Main Authors: Yingjie Xie, Yuan Zhang, Xiaohan Wei, Cheng Zhou, Yajing Huang, Xingwang Zhu, Yongxu Chen, Huihong Wen, Xuhui Huang, Juze Lin, Ziying Wang, Yan Ren, Baochao Fan, Xue Deng, Wei Tan, Changjun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
Jianpi Huayu decoction
hepatocellular carcinoma
immunosuppression
myeloid-derived suppressor cells
maturation
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00016/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00016/full

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