Novel mechanism of arenavirus-induced liver pathology.

Novel mechanism of arenavirus-induced liver pathology.

Viral hemorrhagic fevers (VHFs) encompass a group of diseases with cardinal symptoms of fever, hemorrhage, and shock. The liver is a critical mediator of VHF disease pathogenesis and high levels of ALT/AST transaminases in plasma correlate with poor prognosis. In fact, Lassa Fever (LF), the most pre...

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Bibliographic Details
Main Authors: Juliane I Beier, Jenny D Jokinen, Gretchen E Holz, Patrick S Whang, Amah M Martin, Nikole L Warner, Gavin E Arteel, Igor S Lukashevich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0122839

Internet

https://doi.org/10.1371/journal.pone.0122839

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