EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells

EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells

Although human induced pluripotent stem cells (hiPSCs) hold great potential for the study of human diseases affecting disparate cell types, they have been underutilized in seeking mechanistic insights into the pathogenesis of congenital craniofacial disorders. Craniofrontonasal syndrome (CFNS) is a...

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Bibliographic Details
Main Authors: Terren K. Niethamer, Andrew R. Larson, Audrey K. O’Neill, Marina Bershteyn, Edward C. Hsiao, Ophir D. Klein, Jason H. Pomerantz, Jeffrey O. Bush
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Stem Cell Reports
Subjects:
human induced pluripotent stem cells (hiPSCs)
craniofrontonasal syndrome (CFNS)
EFNB1
Eph/ephrin signaling
cell segregation
cell sorting
X chromosome inactivation (XCI)
neuroepithelial cells
neural progenitor cells
craniofacial
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117300322

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http://www.sciencedirect.com/science/article/pii/S2213671117300322

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