Left ventricular transmural gradient in mitochondrial respiration is associated with increased sub-endocardium nitric oxide and reactive oxygen species productions

Left ventricular transmural gradient in mitochondrial respiration is associated with increased sub-endocardium nitric oxide and reactive oxygen species productions

Objective: Left ventricle (LV) transmural gradient in mitochondrial respiration has been recently reported. However, to date, the physiological mechanisms involved in the lower endocardium mitochondrial respiration chain capacity still remain to be determined.Since nitric oxide (NO) synthase express...

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Bibliographic Details
Main Authors: Michel KINDO, Sebastien GERELLI, Jamal BOUITBIR, Tam HOANG MINH, Anne-Laure CHARLES, Jean-Philippe MAZZUCOTELLI, Joffrey ZOLL, Francois PIQUARD, Bernard GENY
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Physiology
Subjects:
Mitochondria
Mitochondria, Heart
Nitric Oxide
Oxidative Stress
MPTP
transmural
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00331/full

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http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00331/full

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