Regulation of protein function by interfering protein species

Most proteins do not function alone but act in protein complexes. For several transcriptional regulators, it is known that they have to homo- or heterodimerize prior to DNA binding. These protein interactions occur through defined protein-protein-interaction (PPI) domains. More than two decades ago,...

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Bibliographic Details
Main Authors: Graeff Moritz, Wenkel Stephan
Format: Article
Language:English
Published: De Gruyter 2012-02-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc.2011.053