Exploring the Role of ATP-Citrate Lyase in the Immune System

Studies over the past decade have revealed that metabolism profoundly influences immune responses. In particular, metabolism causes epigenetic regulation of gene expression, as a growing number of metabolic intermediates are substrates for histone post-translational modifications altering chromatin...

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Bibliographic Details
Main Authors: Monica Dominguez, Bernhard Brüne, Dmitry Namgaladze
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.632526/full