Detection of <i>EGFR</i> Mutations in Plasma Cell-Free Tumor DNA of TKI-Treated Advanced-NSCLC Patients by Three Methodologies: Scorpion-ARMS, PNAClamp, and Digital PCR

Detection of <i>EGFR</i> Mutations in Plasma Cell-Free Tumor DNA of TKI-Treated Advanced-NSCLC Patients by Three Methodologies: Scorpion-ARMS, PNAClamp, and Digital PCR

Analysis of circulating cell-free tumor DNA (cftDNA) has emerged as a specific and sensitive blood-based approach to detect epidermal growth factor receptor (<i>EGFR</i>) mutations in non-small cell lung cancer (NSCLC) patients. Still, there is some debate on what should be the preferent...

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Bibliographic Details
Main Authors: Annamaria Siggillino, Paola Ulivi, Luigi Pasini, Maria Sole Reda, Elisa Chiadini, Francesca Romana Tofanetti, Sara Baglivo, Giulio Metro, Lucio Crinó, Angelo Delmonte, Vincenzo Minotti, Fausto Roila, Vienna Ludovini
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Diagnostics
Subjects:
<i>EGFR</i>
TKIs
cftDNA
liquid biopsy
NSCLC
Online Access:https://www.mdpi.com/2075-4418/10/12/1062

Internet

https://www.mdpi.com/2075-4418/10/12/1062

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