The gut microbiota modulates glycaemic control and serum metabolite profiles in non-obese diabetic mice.

Islet autoimmunity in children who later progress to type 1 diabetes is preceded by dysregulated serum metabolite profiles, but the origin of these metabolic changes is unknown. The gut microbiota affects host metabolism and changes in its composition contribute to several immune-mediated diseases;...

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Bibliographic Details
Main Authors: Thomas U Greiner, Tuulia Hyötyläinen, Mikael Knip, Fredrik Bäckhed, Matej Orešič
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110359