Induction of Stress-Induced Renal Cellular Senescence In Vitro: Impact of Mouse Strain Genetic Diversity

Induction of Stress-Induced Renal Cellular Senescence In Vitro: Impact of Mouse Strain Genetic Diversity

Cellular senescence, a stress-induced state of irreversible cell cycle arrest, is associated with organ dysfunction and age-related disease. While immortalized cell lines bypass key pathways of senescence, important mechanisms of cellular senescence can be studied in primary cells. Primary tubular e...

Full description

Bibliographic Details
Main Authors: Chieh Ming Liao, Vera Christine Wulfmeyer, Maxine Swallow, Christine Susanne Falk, Hermann Haller, Ron Korstanje, Anette Melk, Roland Schmitt
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
cellular senescence
primary cells
cell culture
genetic background
mouse strains
Online Access:https://www.mdpi.com/2073-4409/10/6/1437

Internet

https://www.mdpi.com/2073-4409/10/6/1437

Similar Items