A dynamical systems hypothesis of schizophrenia.

We propose a top-down approach to the symptoms of schizophrenia based on a statistical dynamical framework. We show that a reduced depth in the basins of attraction of cortical attractor states destabilizes the activity at the network level due to the constant statistical fluctuations caused by the...

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Bibliographic Details
Main Authors: Marco Loh, Edmund T Rolls, Gustavo Deco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2065887?pdf=render