SPAG17 Is Required for Male Germ Cell Differentiation and Fertility

Spag17 encodes a protein present in the axoneme central pair complex of motile cilia and flagella. A mutation in this gene has been reported to be associated with infertility caused by defects in sperm motility. Here, we report that Spag17 knockout mice are infertile because of a severe defect in sp...

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Bibliographic Details
Main Authors: Elizabeth Kazarian, HyunYoung Son, Paulene Sapao, Wei Li, Zhibing Zhang, Jerome F. Strauss III, Maria E. Teves
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/4/1252