Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis

Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition-dependent checkpoint, critical weight. Previous studie...

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Bibliographic Details
Main Authors: Takashi Koyama, Marisa A Rodrigues, Alekos Athanasiadis, Alexander W Shingleton, Christen K Mirth
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/03091