Heparan sulfate functions are altered in the osteoarthritic cartilage

Heparan sulfate functions are altered in the osteoarthritic cartilage

Abstract Background Heparan sulfate (HS) proteoglycans (PG) may be found at the chondrocyte surface and in the pericellular cartilage matrix, and are involved in cell-cell and cell-matrix interactions. An important function of HS chains is to regulate cell fate through specific interactions with hep...

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Bibliographic Details
Main Authors: Sara Shamdani, Sandrine Chantepie, Camille Flageollet, Nadia Henni-Chebra, Yohann Jouan, Florent Eymard, Eric Hay, Martine Cohen-Solal, Dulce Papy-Garcia, Xavier Chevalier, Patricia Albanese
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Arthritis Research & Therapy
Subjects:
Heparan sulfate
Sulfation
Osteoarthritis
Cartilage matrix
Chondrocytes
Online Access:https://doi.org/10.1186/s13075-020-02352-3

Internet

https://doi.org/10.1186/s13075-020-02352-3

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