Gold nanoparticle DNA damage in radiotherapy: A Monte Carlo study

This study investigated the DNA damage due to the dose enhancement of using gold nanoparticles (GNPs) as a radiation sensitizer in radiotherapy. Nanodosimetry of a photon irradiated GNP was performed with Monte Carlo simulations using Geant4-DNA (ver. 10.2) in the nanometer scale. In the simulation...

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Bibliographic Details
Main Authors: James C.L. Chow, Chun He
Format: Article
Language:English
Published: AIMS Press 2016-07-01
Series:AIMS Bioengineering
Subjects:
DNA
Online Access:http://www.aimspress.com/Bioengineering/article/895/fulltext.html