Risk of Cancer in Family Members of Patients with Lynch-Like Syndrome

Lynch syndrome (LS) is a common cause of hereditary colorectal cancer (CRC). Some CRC patients develop mismatch repair deficiency without germline pathogenic mutation, known as Lynch-like syndrome (LLS). We compared the risk of CRC in first-degree relatives (FDRs) in LLS and LS patients. LLS was dia...

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Main Authors: María Dolores Picó, Ana Beatriz Sánchez-Heras, Adela Castillejo, Mar Giner-Calabuig, Miren Alustiza, Ariadna Sánchez, Leticia Moreira, María Pellise, Antoni Castells, Gemma Llort, Carmen Yagüe, Teresa Ramon y Cajal, Alexandra Gisbert-Beamud, Joaquin Cubiella, Laura Rivas, Maite Herraiz, Catalina Garau, Inmaculada Salces, Marta Carrillo-Palau, Luis Bujanda, Adriá López-Fernández, Cristina Alvarez-Urturi, María Jesús López, Cristina Alenda, Pedro Zapater, Francisco Javier Lacueva, Francesc Balaguer, Jose-Luis Soto, Óscar Murcia, Rodrigo Jover
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/8/2225