Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study

Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study

Fenofibrate lowers triglycerides (TG) and raises high density lipoprotein cholesterol (HDLc) in dyslipidemic individuals. Several studies have shown genetic variability in lipid responses to fenofibrate treatment. It is, however, not known whether epigenetic patterns are also correlated with the cha...

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Bibliographic Details
Main Authors: Mithun eDas, Ryan eIrvin, Jin eSha, Stella eAslibekyan, Bertha eHidalgo, Rodney T Perry, Degui eZhi, Hemant K Tiwari, Devin eAbsher, Jose M Ordovas, Donna K Arnett
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Genetics
Subjects:
DNA Methylation
Fenofibrate
cardiovascular disease
Dyslipidemia
Epigenetic changes
Lipid lowering drug
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00304/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00304/full

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