HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma.

We recently reported that HIV-1 infection can be inhibited by innate antimicrobial components of human seminal plasma (SP). Conversely, naturally occurring peptidic fragments from the SP-derived prostatic acid phosphatase (PAP) have been reported to form amyloid fibrils called "SEVI" and e...

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Bibliographic Details
Main Authors: Julie A Martellini, Amy L Cole, Pavel Svoboda, Olga Stuchlik, Li-Mei Chen, Karl X Chai, Bhushan K Gangrade, Ole E Sørensen, Jan Pohl, Alexander M Cole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024420?pdf=render