HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages.

Macrophages act as reservoirs of human immunodeficiency virus type 1 (HIV-1) and play an important role in its transmission to other cells. HIV-1 Vpr is a multi-functional protein involved in HIV-1 replication and pathogenesis; however, its exact role in HIV-1-infected human macrophages remains poor...

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Bibliographic Details
Main Authors: Muhammad Atif Zahoor, Guangai Xue, Hirotaka Sato, Tomoyuki Murakami, Shin-nosuke Takeshima, Yoko Aida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149569?pdf=render