HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages.
Macrophages act as reservoirs of human immunodeficiency virus type 1 (HIV-1) and play an important role in its transmission to other cells. HIV-1 Vpr is a multi-functional protein involved in HIV-1 replication and pathogenesis; however, its exact role in HIV-1-infected human macrophages remains poor...
Main Authors: | Muhammad Atif Zahoor, Guangai Xue, Hirotaka Sato, Tomoyuki Murakami, Shin-nosuke Takeshima, Yoko Aida |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4149569?pdf=render |
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