Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19
Pluripotent stem cells can be stabilized in vitro at different developmental states by the use of specific chemicals and soluble factors, of which the naïve and primed states are the best characterized. Naïve pluripotent stem cells (PSCs) correspond to the early pre-implantation blastocyst and, in m...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/4/876 |