Network-Guided Discovery of Influenza Virus Replication Host Factors

Network-Guided Discovery of Influenza Virus Replication Host Factors

Integrating virus-host interactions with host protein-protein interactions, we have created a method using these established network practices to identify host factors (i.e., proteins) that are likely candidates for antiviral drug targeting. We demonstrate that interaction cascades between host prot...

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Bibliographic Details
Main Authors: Emily E. Ackerman, Eiryo Kawakami, Manami Katoh, Tokiko Watanabe, Shinji Watanabe, Yuriko Tomita, Tiago J. Lopes, Yukiko Matsuoka, Hiroaki Kitano, Jason E. Shoemaker, Yoshihiro Kawaoka
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
drug targets
influenza
protein-protein interactions
virus-host interactions
Online Access:https://doi.org/10.1128/mBio.02002-18

Internet

https://doi.org/10.1128/mBio.02002-18

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