Two-Carbon Homologation of Aldehydes and Ketones to α,β-Unsaturated Aldehydes

Phosphonate reagents were developed for the two-carbon homologation of aldehydes or ketones to unbranched- or methyl-branched α,β-unsaturated aldehydes. The phosphonate reagents, diethyl methylformyl-2-phosphonate dimethylhydrazone and diethyl ethylformyl-2-phosphonate dimethylhydrazone, contained a...

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Bibliographic Details
Main Authors: Allard A. Cossé, Richard J. Petroski, Karl Vermillion
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/6/5062/