Chemotactic and Angiogenic Potential of Mineralized Collagen Scaffolds Functionalized with Naturally Occurring Bioactive Factor Mixtures to Stimulate Bone Regeneration

Chemotactic and Angiogenic Potential of Mineralized Collagen Scaffolds Functionalized with Naturally Occurring Bioactive Factor Mixtures to Stimulate Bone Regeneration

To develop cost-effective and efficient bone substitutes for improved regeneration of bone defects, heparin-modified mineralized collagen scaffolds were functionalized with concentrated, naturally occurring bioactive factor mixtures derived from adipose tissue, platelet-rich plasma and conditioned m...

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Bibliographic Details
Main Authors: Henriette Bretschneider, Mandy Quade, Anja Lode, Michael Gelinsky, Stefan Rammelt, Corina Vater
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
growth factor
bone regeneration
collagen scaffold
bone substitute materials
MSC secretome
hypoxia-conditioned medium
Online Access:https://www.mdpi.com/1422-0067/22/11/5836

Internet

https://www.mdpi.com/1422-0067/22/11/5836

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