Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process.

A reproducible method to inhibit allergic immune responses is accomplished with hi-dose Ag sensitization, via intraperitoneal (IP) injection. However, the role of CD4+ CD25+ FoxP3+ T regulatory cells (Treg) in this process is unknown, as is whether such modulation extends to ocular allergy. We there...

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Bibliographic Details
Main Authors: Hyun Soo Lee, Simona Schlereth, Payal Khandelwal, Daniel R Saban
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3785421?pdf=render