The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain

The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain

Nerve injury-induced neuropathic pain is difficult to treat and mechanistically characterized by strong neuroimmune interactions, involving signaling lipids that act via specific G-protein coupled receptors. Here, we investigated the role of the signaling lipid receptor G2A (GPR132) in nerve injury-...

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Bibliographic Details
Main Authors: Tabea Osthues, Béla Zimmer, Vittoria Rimola, Kevin Klann, Karin Schilling, Praveen Mathoor, Carlo Angioni, Andreas Weigert, Gerd Geisslinger, Christian Münch, Klaus Scholich, Marco Sisignano
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
neuropathic pain
9-HODE
oxidized linoleic acid metabolites
macrophage migration
G2A
GPR132
Online Access:https://www.mdpi.com/2073-4409/9/7/1740

Internet

https://www.mdpi.com/2073-4409/9/7/1740

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