Modeling for influenza vaccines and adjuvants profile for safety prediction system using gene expression profiling and statistical tools.

Historically, vaccine safety assessments have been conducted by animal testing (e.g., quality control tests and adjuvant development). However, classical evaluation methods do not provide sufficient information to make treatment decisions. We previously identified biomarker genes as novel safety mar...

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Bibliographic Details
Main Authors: Eita Sasaki, Haruka Momose, Yuki Hiradate, Keiko Furuhata, Mamiko Takai, Hideki Asanuma, Ken J Ishii, Takuo Mizukami, Isao Hamaguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5800680?pdf=render