Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Abstract The physiological functions controlled by T-type channels are intrinsically dependent on their gating properties, and alteration of T-type channel activity is linked to several human disorders. Therefore, it is essential to develop a clear understanding of the structural determinants respon...

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Bibliographic Details
Main Authors: Bohumila Jurkovicova-Tarabova, Leos Cmarko, Renata Rehak, Gerald W. Zamponi, Lubica Lacinova, Norbert Weiss
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-019-0457-0