CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice
Abstract Background Inhibition of CD4 T cells reduces stroke-induced infarction by inhibiting neuroinflammation in the ischemic brain in experimental stroke. Nevertheless, little is known about its effects on neuronal survival signaling pathways. In this study, we investigated the effects of CD4 T c...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Chinese Neurosurgical Journal |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41016-018-0140-9 |