CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice

Abstract Background Inhibition of CD4 T cells reduces stroke-induced infarction by inhibiting neuroinflammation in the ischemic brain in experimental stroke. Nevertheless, little is known about its effects on neuronal survival signaling pathways. In this study, we investigated the effects of CD4 T c...

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Bibliographic Details
Main Authors: Hongfei Zhang, Xiaoxing Xiong, Lijuan Gu, Weiying Xie, Heng Zhao
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Chinese Neurosurgical Journal
Subjects:
Akt
Online Access:http://link.springer.com/article/10.1186/s41016-018-0140-9